A236
 |  |  |
 |
Image
Useful Links & Tools
- MSDS
- Certificate of Analysis
- A236 - Datasheet (51 KB)
- Bulk Quote
- Similar Products
Last 5 Products Viewed
A236
Sigma
AB-MECA
solid
| Synonym: | N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine, N6-(4-Aminobenzyl)-9-[5-(methylcarbonyl)-β- |
| CAS Number: | 152918-26-8 |
| Linear Formula: | C18H21N7O4 |
| Molecular Weight: | 399.40 |
| PubChem Substance ID: | 24277694 |
Description
| Biochem/physiol Actions | High affinity A3 adenosine receptor agonist. |
| Legal Information | Sold under license from the National Institutes of Health. |
Properties
| form | solid |
| color | off-white |
| solubility | 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.3 mg/mL |
| ethanol: 1 mg/mL | |
| DMSO: 10 mg/mL | |
| dilute aqueous base: 3.5 mg/mL | |
| H2O: insoluble | |
| Gene Information | human ... ADORA3(140) |
| rat ... Adora1(29290), Adora2a(25369), Adora3(25370) | |
| storage temp. | −20°C |
Safety
| Personal Protective Equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
| WGK Germany | 3 |
References
| reference | Olah, et al., 125I-4-Aminobenzyl-5′-N-methylcarboxamidoadenosine, a high affinity radioligand for the rat A3 adenosine receptor. Mol. Pharmacol. 45, 978-982, (1994) Abstract |
| Gallo-Rodriguez, et al., Structure-activity relationships of N6-benzyladenosine-5′-uronamides as A3 selective adenosine agonists. J. Med. Chem. 37, 636-646, (1994) Abstract | |
| Jacobson, et al., A role for central A3-adenosine receptors. Mediation of behavioral depressant effects. FEBS Lett. 336, 57-60, (1993) Abstract |
